If possible you should reserve a separate area for your home office. It needs to be big enough to hold all necessary equipment, as well as your day-to-day filing. It should be private enough to ensure you are free from constant interruptions and distracting noise.Freedom from distraction is not just a design issue. Consider setting "working hours" when other occupants of the home know they should generally leave you alone. As a rule of thumb, if you need to make care arrangements in order to go to an office job, then you'll need similar arrangements to give you the time to work at home.
Although it's conceivable that some kinds of work can be performed from home with little more than a telephone, in practice you are likely to require a good personal computer with a modem, and possibly a separate fax machine.
Your home office should meet the kind of health and safety standards that you would expect in a normal office. Health and safety regulations are more like a guide to good practice. After all, it is your health at stake and the 1992 regulation on the display screen equipment is particularly important if you plan to spend much time in front of your PC.